Fertility Infertility Issues

It is heartbreaking when in vitro fertilization (IVF) failure occurs. Prospective parents desperately want to know what happened, but it is not always possible to pinpoint the exact cause. There are a variety of factors that could have played a part in the lack of success of the attempt, and these include the following factors.

Lower quality of eggs due to advanced age of the mother

As women get older, they do not have as many eggs in their ovaries as in their youth. In addition, the quality of those eggs can decrease. They may be more likely to have abnormalities that would result in an problematic pregnancy and subsequent failed attempt. As a woman progresses through her thirties her chances of a successful IVF attempt decreases.

Poor response of the ovaries

During IVF, the hope is that the woman will produce a lot of eggs. During the process, women may be given medication to help them produce more follicles, however not every woman’s ovaries respond well and produce as many eggs as needed for success. Again, various factors may cause this. If the woman is greater in age than 37, she is more likely to have fewer follicles. If she has elevated FSH hormones, then this can cause a stunting as well. Also, if she does not have as many eggs remaining in her ovaries then fewer may be produced.

Failure is likely if two or fewer mature follicles occur. One option to combat this is to use aggressive superovulation with high doses of HMG. There are risks associated with this, which should be thoroughly researched before this method is chosen.

Difficult transfer

Sometimes the transfer of the egg is difficult, and bleeding occurs. Cervical stenosis can cause problems that make the IVF fail. To go around this, one option is a fallopian tube transfer. In this way the cervix can be bypassed.

Problems with implantation

Even if fertilization occurs, the IVF attempt may be unsuccessful if implantation does not properly occur. For instance, the woman may have an issue with polyps or fibroids in her uterus.

Sometimes the embryo simply stop growing. This can be caused by a wide range of factors. There may be a genetic defect that does not allow the embryo to develop normally. The egg may not implant correctly, or a miscarriage may occur.

The positive news is that many couples go on to have successful IVF experiences, even after failures. Prospective parents should talk with their medical providers to learn more about the issues that may affect their particular case and the other options they have. With luck, their dream will soon come true.

Resources:

http://www.fertilityauthority.com/diagnosis/ivf-failure

http://www.drmalpani.com/failedivf.htm

http://www.ivf.com/overview.html